Selected
Publications
Wong M.K.K., Prudovsky,
I., Vary, C., Booth, C.,
Liaw, L., Mousa, S., Small, D., and Maciag, T., A
Non- Transmembrane Form of Jagged-1 Regulates the Formation of
Matrix-Dependent Chord-like Structures. Biochem. Biophys. Res.
Commun., 2000; 268:853-859.
Landricina, M., Prudovsky, I., Mouta Carreira, C., Tarantini, F., Maciag, T., Amlexanox
Reversibly Inhibits Cell Migration and Proliferation and Induces the Src-Dependent
Disassembly of Actin Stress Fibers In Vitro, J. Biol. Chem, 2000; 275:32753-32762.
Prudovsky, I., Landriscina, M., Soldi, R., Bellum, S., Small, D., Andreeva, V.,
Maciag, T., Fusions
to members of fibroblast growth factor gene family to study nuclear translocation
and nonclassic exocytosis. Methods in Enzymology 2000; 327:369-382
Tarantini, F., Micucci, I., Bellum, S., Landriscina, M., Garfinkel, S., Prudovsky,
I., and T. Maciag. The
Precursor But Not the Mature Form of IL1• Blocks the Release of FGF1 in
Response to Heat Shock, J. Biol. Chem., Rapid Commun., 2001; 276:5147-5151.
Landriscina, M., Soldi, R., Bagalá, Micucci, I., Bellum, S., Tarantini,
F., Prudovsky, I., and Maciag, T. S100A13
Participates in the Release of Fibroblast Growth Factor 1 in Response to Heat
Shock in Vitro. J. Biol. Chem., 2001; 22544-22552.
Lindner, V., Booth, C., Prudovsky, I., Small, D., Maciag, T., Liaw, L., Members
of the jagged/Notch Gene Families are expressed in Injured Arteries and Regulate
Cell Phenotype via Alterations in Cellmatrix and Cell-cell Interactions.
Am. J. Pathol., 2001; 159: 875-883.
Landriscina, M., Bagala, C., Mandinova, A., Soldi, R., Micucci, I., Bellum, S,
Prudovsky, I., and Maciag, T. Copper
Induces the Assembly of a Multiprotein Aggregate Implicated in the Release of
FGF1 in Response to Stress. J. Biol. Chem., 2001; 276:25549-25557.
Small, D., Kovalenko, D., Kacer, D., Liaw, L., Landriscina, M., Di Serio, C.,
Prudovsky, I., Maciag, T., Soluble
Jagged 1 Represses the Function of Its Transmembrane Form to Induce the Formation
of the Src-dependent Chord-like Phenotype; J. Biol. Chem., 2001; 276:32022-32030.
Mouta-Carreira, C., Landriscina, M., Prudovsky I and Maciag, T. The
Comparative Release of FGF1 by Hypoxia and Temperature Stress. Growth Factors,
2001; 18:277-285.
Mandinov, L., Mandinova, A., Kyurkchiev, S., Kyurkchiev, D., Kehayov,
I., Kolev, V., Soldi, R., Bagalá, C., deMuinck, E.D., Lindner,
V., Post, M.J., Simons, M., Bellum, S., Prudovsky, I. and Maciag, T. Copper
Chelation Represses the Vascular Response to Injury. Proc. Natl. Acad. Sci.,
U.S.A. 2003; 100:6700-6705.
Small, D., Kovalenko, D., Soldi, R., Mandinova, A., Kolev, V., Trifonova,
R., Bagalá, C., Kacer, D., Liaw, L., Prudovsky, I. and Maciag,
T. Notch
Activation Suppresses FGF-Dependent Cellular Transformation. J. Biol. Chem.
2003; 278:16405-16413.
Mandinova, A., Bellum, S., Bagalá, C., Soldi, R., Landriscina,
M., Tarantini, F., Prudovsky, I. and Maciag, T., S100A13
mediates the Copper-Dependent Stress-Induced Release of IL1 from Both Human U937
and Murine NIH 3T3 Cells. J. Cell Sci. 2003; 116:2687-2696.
Mandinov, L., Mandinova, A., Soldi, R., Graziani, I., Bagalá,
C., Prudovsky, I, and Maciag, T. Interleukin
1: The Choreographer for the Restenotic Ballet. Throm. & Haem., 2003;
90:369-371.
Prudovsky, I., Mandinova, A., Soldi, R., Bagalá, C., Graziani,
I., Landriscina, M., Tarantini, F., Duarte, M., Bellum, S., Doherty,
H. and Maciag, T. The
Non-Classical Export Routes: IL1 and FGF1 Point the Way. J. Cell Sci. 2003;
118:4871-81.
Bagala, C., Kolev, V., Mandinova, A., Soldi, R., Mouta, C., Graziania, I., Prudovsky,
I. and Maciag. T. The
Alternative Translation of Synaptotagmin 1 Mediates the Non-Classical Release
of FGF1. BBRC, 2003; 310(4):1041-7.
Doyle, A., Fick, J., Himmelhaus, M., Eck, W., Graziani,
I., Prudovsky, I., Grunze, M., Maciag, T., Neivandt,
D. Protein
Deformation of Lipid Hybrid Bilayer Membranes Studied by Sum Frequency
Generation Vibrational Spectroscopy (SFS). Langmuir, 2004; 20:8961-8965.
Andreeva, V., Prudovsky, I.,
Maciag, T. Stimulation
of Quiescent Cells by Individual Polypeptide Growth Factors is
Limited to One Cell Cycle. Eur. J. Cell,
Biol., 2004; 83:327-35.
Trifonova, R., Small., D, Kacer., D, Kovalenko, D.,
Kolev, V., Mandinova, A., Soldi. R., Liaw, L., Prudovsky,
I., Maciag, T. The
Non-Transmembrane Form of Delta1 but not of Jagged1 Induces Normal
Migratory Behavior Accompanied by FGF Receptor 1-Dependent Transformation. J. Biol. Chem., Accel.
Publ., 2004; 279:13285-88.
Peng. H., Sahni, A., Fay, P.J., Bellum, S., Prudovsky,
I., Maciag, T.; Francis, CW. Identification
of a Binding Site on Human FGF-2 for Fibrinogen. Blood, 2004; 103:2114-2120.
Omoto, A., Kawahito, Y., Prudovsky, I.,
Tubouchi, Y., Kimura, M., Ishino, H., Wada, M., Yoshida, M., Yoshimura,
R., Yoshikawa, T., Sano, H.. Copper
Chelation with Tetrathiomolybdate Suppresses Adjuvant-Induced Arthritis
and Inflammation-Associated Cachexia in Rats. Arthritis Research and Therapy, 2006; 7:R1174-1182.
Sivaraja, V., Kumar, TKS, Prudovsky, I.,
Yu, C. Three-Dimensional
Solution Structure of Mouse S100A13, a Component of the Fibroblast
Growth Factor 1 Non-Classical Release Pathway. Biochem. Biophys. Res. Commun., 2005; 335:1140-1148.
Kolev, V., Kacer, D., Trifonova, R., Small, D., Duarte,
M., Soldi, R., Graziani, I., Sideleva, O., Larman, B., Maciag,
T., Prudovsky, I.. The
Intracellular Domain of Notch Ligand Delta1 Induces Cell Growth
Arrest. FEBS Letters,
2005; 579:5798-5802.
Rajalingam,
D., Kumar, TKS, Soldi, R., Graziani, I., Prudovsky, I.,
Yu, C.. Molecular
Mechanism of Inhibition of Non-Classical FGF-1 Export. Biochemistry,
2005; 44:15472-15479.
Sivaraja, V., Kumar, TKS., Rajalingam., Graziani,
I., Prudovsky, I., Yu, C. Copper
Binding Affinity of S100A13, a Key Component of the FGF-1 Non-Classical
Copper-Dependent Release Complex. Biophys. J., 2006; 91:1-12.
Landriscina, M., Schinzari, G., Di Leonardo, G.,
Quirino, M., Cassano, A., D'Argento, E., Lauriola, L., Scerrati,
M., Prudovsky, I., Barone, C. S100A13,
a New Marker of Angiogenesis in Human Astrocytic Gliomas. J Neurooncol, 2006;
80: 251-259.
Graziani, I., Bagala, C., Duarte, M., Soldi, R.,
Kolev, V., Tarantini, F., Kumar, S., Doyle, A., Neivandt, D., Yu,
C., Maciag, T., Prudovsky, I. Release
of FGF1 and p40 Synaptotagmin 1 Correlates with Their Membrane
Destabilizing Ability. Biochem. Biophys. Res. Commun., 2006; 349:192-9.
Duarte,
M., Kolev, V., Soldi, R., Kirov, A., Oliveira,
SM, Graziani, I., Kacer, D., Friesel, R.., Maciag, T., Prudovsky,
I. Thrombin
Induces Rapid PAR1-Mediated Non-Classical FGF1 Release. Biochem. Biophys. Res. Commun., 2006; 350:604-9.
Di Serio, C., Pellerito, S., Duarte, M., Massi, D.,
Naldini, A., Cirino, G., Prudovsky, I., Santucci,
M., Geppetti, P., Marchionni, N., Masotti, G., Tarantini, F. Protease-Activated
Receptor (PAR) 1 Selective Antagonist SCH7997 Inhibits Cell Proliferation
and Induces Apoptosis, by a PAR-1 Independent Mechanism. Basic
Clin. Pharmacol. Toxicol., 2007; 101:63-69.
Soldi, R., Mandinova, A., Venkataraman, K., Hla,
T., Vadas, M., Pitson, S., Duarte, M., Graziani, I., Kolev, V.,
Kacer, D., Kirov, A., Maciag, T. Prudovsky, I.
Sphingosine
Kinase 1 is a Critical Component of the Copper-Dependent FGF1 Export
Pathway. Exper. Cell Res., 2007; 313: 3308-3318.
Rajalingam, D., Graziani, I., Prudovsky,
I., Yu, C., Kumar, TKS. Relevance
of Partially Structured States in the Non-Classical Secretion
of Acidic Fibroblast Growth Factor. Biochemistry, 2007; 46; 9225-9238.
Rajalingam, D., Kacer, D., Prudovsky, I.,
Kumar, TKS. Molecular
Cloning, Overexpression and Characterization of Interleukin 1 alpha. Biochem. Biophys. Res. Commun., 2007; 360:
604-608.
Kathir, K, Ibrahim, K., Rajalingam, D., Prudovsky,
I., Yu, C., Kumar TKS. S100A13-Lipid
Interactions Role in the Non-Classical Release of the Acidic
Fibroblast Growth Factor. Biochim. Biophys. Acta, ,2007; 1768: 3080-3089.
Nikopoulos, G., Duarte, M., Kubu, C., Bellum, S.,
Friesel, R., Maciag, T., Prudovsky, I., Verdi,
J., Soluble
Jagged1 Attenuates Lateral Inhibition, Allowing for Expansion of
Neural Crest Stem Cells. Stem Cells, 2007; 25: 3133-3142.
Prudovsky, I.,
Tarantini, F., Landriscina, M., Neivandt, D., Soldi, R., Kirov, A., Small, D., Kathir,
KM, Rajalingam D., Kumar, TKS. Secretion
Without Golgi. J
Cell. Biochem., 2008; 3: 1327-1343.
Leclair, RJ, Wang, Q, Benson, MA, Prudovsky,
I, Lindner, V. Intracellular
Localization of Cthrc1 Characterizes Differentiated Smooth Muscle
Cells". Arterioscler
Thromb Vasc Biol., 2008; 28:1332-1338.
Lee, CW, Raskett, CM, Prudovsky, I,
Altieri, DC. Molecular
Dependence of Estrogen Receptor-Negative Breast Cancer on a Notch-Survivin
Signaling Axis. Cancer Res.,
2008, 68: 5273-81.
Di Serio, C, Doria, L, Pellerito, S, Prudovsky,
I, Micucci, I, Massi , D, Landriscina, M, Marchionni,
N, Masotti, G., Tarantini, F. The
Release of Fibroblast Growth Factor-1 from Melanoma Cells Requires
Copper Ions and is Mediated by Phosphatidylinositol 3-kinase/Akt
Intracellular Signaling Pathway. Cancer Letters, 2008, 267:67-74.
Nikopoulos, GN, Adams, TL, Adams, D, Oxburgh, L, Prudovsky,
I, Verdi, JM. The
Use of Endo-Porter to Deliver Morpholinos in Kidney Organ Culture. Biotechniques, 2008: 44: 547-549.
Duarte,
M, Kolev, V, Kacer, D, Mouta-Bellum, C, Soldi, R, Graziani, I,
Kirov, A, Friesel, R, Liaw, L, Small, D, Verdi, J, Maciag, T,
Prudovsky, I. Novel
Cross-Talk between Three Cardiovascular Regulators: Thrombin
Cleavage Fragment of Jagged 1 Induces FGF1 Expression and Release,
2008, Mol. Biol. Cell. Epub ahead of print. |
