Amanda (Rago) Sedgewick

Chief Resident in Pyschiatry, Maine Medical Center


BA: Simmons College
MS: in Bioinformatics: Boston University
DO: University of New England College of Osteopathic Medicine
Post-Doctoral Training:   Department of Psychiatry, Maine Medical Center, Tufts University School of Medicine

Dr. Amanda Sedgewick is an osteopathic physician, and Chief Resident in Psychiatry at Maine Medical Center with a focus on research and quality improvement.  She has a Master’s degree in Bioinformatics from Boston University and previously worked in this field as a research assistant at Boston University Medical Center and School of Public Health under Dr. Paola Sebastiani, and at Harvard Medical School, and Children’s Hospital Informatics Program under Dr. Marco Ramoni.  She attended medical school at the University of New England, College of Osteopathic Medicine, and is currently completing the last year of her residency in Adult Psychiatry at Maine Medical Center.

Her clinical work at Maine Medical Center is based currently on outpatient (less frequently inpatient) care of psychiatric patients.  Her particular areas of interest include addiction psychiatry and medication assisted treatment both in the individual and group settings, as well as patients with a history of trauma, PTSD, and exposure to Intimate Partner Violence.   Her research interest includes development of a project working with groups in the Southern Maine area such as Family Crisis Services and Caring Unlimited, with hopes to begin providing accessible psychiatric care to patients in these situations.  She is a member of the advisory group through the Maine Coalition to End Domestic Violence social work curriculum development project working towards developing training modules for providers throughout the state of Maine.   She is also PI on several other studies related to ECT in patients with dementia with behavioral disturbance, and depression in post-MI patients.

S. Klings, D. A. Dworkis, A. Sedgewick, S. W. Hartley, A. Ashley-Koch, M. J. Telen, G. J. Kato, M. T. Gladwin, P. Sebastiani, C. Baldwin, M. H. Steinberg. Association of Genetic Polymorphisms In NEDD4L With Pulmonary Hypertension Of Sickle Cell Disease. Am J Respir Crit Care Med 181;2010: A4881.

Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang M, Melista E, Meltzer M, Fischer S, Andersen S, Hartley SH, Sedgewick AE, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Viviani C, Anselmi, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo T, Steinberg MH6, Hirose N, Atzmon G, Ruvkun G, Baldwin C, Perls T. RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans. PLoS ONE 2009; 4(12): e8210.

Amanda E. Sedgewick, Nadia Timofeev, Paola Sebastian, Jason C.C. So, Edmond S.K. Ma, Li Chong Chan, Goonnapa Fucharoen, Supan Fucharoen, Cynara G. Barbosa, Badri N. Vardarajan, Lindsay A. Farrer, Clinton T. Baldwini, Martin H. Steinberg, David H.K. Chui . BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies. Blood Cells Mol Dis. 2008 Aug   6.

Paola Sebastiani, Zhenming Zhao, Maria Abad-­‐Grau, Alberto Riva, Steven Hartley, Amanda Sedgewick,   Alessandro Doria, Monty Montano, Efthymia Melista, Dellara Terry, Thomas T Perls, Martin H Steinberg, Clinton T Baldwin. A Hierarchical and Modular Approach to the Discovery of Robust Associations in Genome-Wide Association Studies from Pooled DNA Samples. BMC Genetics 2008, 9:6.


Professional Activities

  • Chief Resident Of Psychiatry, focus in Research and Quality Improvement
  • Medical Records Committee, Resident Representative, Maine Medical Center
  • Inpatient SeHR Optimization Committee, Resident Representative
  • Advisory Board Member, Maine Coalition to End Domestic Violence’s (MCEDV) curriculum development project

Professional Society Membership

  • American Psychiatric Association
  • American Academy of Addiction Psychiatry
  • Maine Association of Psychiatric Physicians
  • Sigma Xi