Mouse Transgenic & Gene Targeting

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Mouse Transgenic & Gene Targeting 2016-12-07T16:33:52+00:00

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The Mouse Transgenic Core Facility provides a series of high quality services related to mouse genetics, manipulation of mouse embryos, re-derivation and cryopreservation, and the stocking and distribution of shared mouse strains.

We have expertise in generating transgenic mice and gene targeted mice, and performs oocyte, morula, and blastocyst injections. The requesting investigator provides purified, prepared DNA constructs for transgenic injections.

Services Available

  • CRISPR/Cas technology to generate novel mouse models
  • CRISPR/Cas mediated genome modification in mice.
  • Cryopreservation program for mouse embryos and sperm
  • In vitro fertilization or embryo transplantation to recover mouse strains.
User Tg/ CRISPR/ Injection/ day ES Cell Injection/day Rederive/strain Embryo Freeze/day
Internal Fee $  400 $  400 $ 300 $  300
Tufts/IDeA funded investigator $1,200 $1,400 $ 800 $1,000
External Fee Other $1,500 $1,750 $1,000 $1,250
User Sperm Freeze/day
IVF/ experiment
Thawing/implant
Internal Fee $100 $   300 $200
Tufts/IDeA funded investigator $250 $1,000 $600
External Fee Other $325 $1,250 $720

NOTE: Requesting investigator is responsible for mouse purchase, shipping and housing costs.

Please contact Lucy Liaw (liawl@mmc.org) to discuss your mouse transgenic project.

Contact Us

Director: Lucy Liaw, PhD
liawl@mmc.org

Manager: Anne Harrington
harria@mmc.org