Frequently Asked Questions

Frequently Asked Questions 2016-11-17T13:59:40+00:00

The MMC IACUC promotes the humane care of animals used in biomedical research, teaching, and testing; provides information that will enhance animal well-being, the quality of biomedical research, and the advancement of biologic knowledge that is relevant to humans or animals; and advises the Associate Vice President for Research (the Institutional Official responsible for the Animal Care and Use Program) regarding MMC’s institutional compliance with federal regulations and guidelines.

The MMC IACUC is responsible for: reviewing ALL proposed uses of live vertebrate animals in teaching, research, exhibition, and testing, including regular review of all ongoing projects; inspecting the MMCRI animal facilities at least once every six months; reviewing the MMCRI Animal Care and Use Program every six months; submitting semiannual reports based on the semiannual inspections and program reviews to the Associate Vice President for Research; submitting an annual report to the National Institutes of Health’s Office of Laboratory Animal Welfares (OLAW), detailing changes in the animal care and use program, changes in IACUC membership, and the results of the semiannual inspections and program reviews; educating and training personnel involved in animal projects; investigating all concerns involving the care and use of animals at MMCRI; suspending previously approved animal-related activity if the committee determines that the activity is not being conducted in compliance with the Animal Welfare Act, PHS policy, or MMC/MMCRI policy; and making recommendations to the Associate Vice President for Research regarding the Animal Care and Use Program, MMCRI animal facilities, and the care and use training programs available to MMC/MMCRI personnel.

The IACUC must review ALL projects involving the use of ANY vertebrate animals for ANY purpose (including, but not limited to, agricultural, biomedical, and behavioral research, teaching, testing, and exhibition projects) to ensure compliance with MMC/MMCRI policy and federal regulations.

Any faculty or staff member who is the Principal Investigator or Director for any animal activity must submit an IACUC protocol. Students who will be conducting an animal project (e.g. for a thesis project) should submit the project in collaboration with their faculty adviser. Such student protocols should be submitted with the adviser listed as the Principal Investigator and the student listed as the Co-Principal Investigator.

Either a new protocol form or an amendment form may be submitted for review.  Amendment forms are only submitted to seek approval for changes to a previously approved IACUC protocol. Each person involved with the project must also make available documentation that they have completed required training courses for working with animals.
All forms are available online under the “Forms” IACUC section of this website. The website forms are frequently updated. It is important to always use the most current IACUC approved forms.

All paperwork must be submitted and approvals granted BEFORE any work with animals is initiated.  Completed applications must be submitted to the Research Compliance Office no later than 14 business days prior to the meeting.  There is a designated review process for amendments and continuing reviews between meetings, please contact the Research Compliance Office for more information.

The length of the review period may vary from 14 business days to several weeks, depending on the nature of the project, meeting dates, and revision requests. The Research Compliance Office can answer questions about the review process and the amount of time it may require.
It is IACUC policy to allow the PI three weeks to respond to an IACUC request for revisions.  If no response is received within this time period, the submission will not be processed and closed.
All IACUC forms and paperwork should be submitted to the Office of Research Compliance.
The committee meets every month of the year, and will convene for special meetings as the need arises.
A letter of approval is issued 2 – 4 days business days after approval.  You may call the Research Compliance Coordinator for IACUC to obtain information as well.
Project approval is good for 1 year from the date of the approval. All projects are required to be renewed annually.
You may start using animals immediately, if you have been granted full approval.
The PI is the responsible party to remember when the protocol will expire. A notification is sent only as a courtesy by the compliance office, time permitting.
The PI should fill out the IACUC Closure Notice form and return it to the Research Compliance Office.

You must submit an Amendment form and receive IACUC approval prior to initiating any changes to your current protocol. By federal law and MMC/MMCRI Policy, PIs are required to notify the committee of any changes made to any currently active protocol. Typical changes may include, project personnel, numbers and species of animals, modifications to the experimental methods or procedures, special requirements for animal husbandry and housing, etc.