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Faculty Scientist II- Health Outcomes/Health Services Research

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Job Details

  • The ideal candidate for this position will be a health outcomes researcher with a substantive focus in one or more of the following areas: health communication, decision sciences/medical decision making, health services research, or a related field of inquiry.
  • Mid-career researchers with an established program of research and a strong track record of extramural funding and peer-reviewed publications are preferred; however, early career candidates with appropriate skills and experience will be considered.
  • Candidates with an MD/DO, PhD, ScD, DrPH, or other relevant doctoral degree will be considered for this position. For physician-scientists, candidates with formal research training (e.g., MPH, research fellowship) are strongly preferred.

Position Summary

Conducts a variety of research activities, often heading projects independently, but may enlist the assistance of more experienced scientists as collaborators. This position will receive mentorship from one or more senior scientists in areas such as grant writing and applications, teaching, and navigating research administration and research compliance issues. This position will be responsible for the independent conception of research projects, obtaining external funding for these projects and the publication of results from these projects in a timely manner. These studies should be of sufficient importance and impact to bring recognition to the investigator, resulting in increased or sustained funding, etc. This individual will assist in the development of operational guidelines for the research. As an independent position, the individual should exercise good judgment in decision making with regard to the management of personnel, budgets, and other matters that pertain to running a program or project as an independent investigator. With regard to problem-solving, the individual in this position should know the limitations of his or her problem solving skills both scientifically and administratively and should use good judgment to seek advice and input from reliable sources when the problem is beyond the scope of his or her expertise. Follows safety, human subjects and animal use guidelines. Manages grants or projects including supervision of multiple staff, project reports, etc. Monitors the project budget. Where inventions or other intellectual property are developed during the course of the research, will contribute to the process of working with the patents and licensing office to seek appropriate rights. Ability to supervise and to coordinate efforts of several staff for complex internal/external groups. Position availability is directly related to grant funding.

Minimum Knowledge, Skills, and Abilities Required

  • Demonstrated ability to read, write, and speak English effectively
  • Excellent written and verbal communication skills
  • Outstanding interpersonal skills
  • Visual acuity, manual dexterity, math skills and a scientific acumen are required.
    Doctoral degree in relevant biomedical discipline
  • 5 years of experience as a Faculty Scientist I (or Assist Prof)
    Successful track record of R01 funding or equivalent research support
  • First or Senior author publications in major peer-reviewed biomedical journals
  • Evidence of beginning of national recognition in selected field as demonstrated by invited presentations at national biomedical meetings and invited reviews for major biomedical publications
  • Demonstrated ability to design and conduct novel and potentially high impact biomedical experiments
  • Evidence of significant mentorship and teaching accomplishments
  • Evidence of significant institutional citizenship

Essential Functions

  • Supervises major research project(s) and writes grants and obtains extramural funding for major research projects.
  • Ensures timely, accurate and complete communication of research findings at regional, national and international meetings and in major and specialty-specific biomedical journals.
  • Teaches and mentors (as assigned by Center Director) summer students, interns, graduate student and research fellows.
  • Serves on Institutional committees (as assigned by Director, MMCRI) and participates in regional and national professional societies and activities.
  • Ensures compliance with all state and federal regulations pertaining to safety, the ethical conduct of research, financial reporting to funding agencies, and standards of professional conduct.
  • Promotes teamwork and collaboration within MMCRI and with outside institutions.

Project Manager –  Clinical Trials Office

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Position Summary

The Project Manager has primary responsibility for facilitating the planning, implementation and post implementation phases of various strategic projects for the department, and/or Maine Medical Center and/or at participating regional hospitals. The Project Manager will determine the appropriate qualitative and quantitative measures to evaluate progress and successful implementation. These projects will result in measurable improvements that will impact clinical, administrative, financial systems, and/or the infrastructural systems of MMC and that will benefit our patients, families and staff. The Project Manager will also provide regular progress reporting to his/her supervisor and other groups as appropriate.

Minimum Knowledge, Skills, and Abilities Required

  1. Bachelor’s degree in a related field. Master’s preferred. May accept a combination of management and technical experience which is usually acquired through the completion of a Bachelor’s Degree program.
  2. Three to five+ year’s project management experience that is multidisciplinary in nature.
  3.  A high level of interpersonal skills are necessary to support dynamic work teams and communicate effectively with a wide variety of patients/families, hospital administrative staff, clinicians and external contacts and vendors.
  4.  A high level of analytical and critical thinking skills are needed to assist in the development of new systems, techniques, procedures and to develop special and recurring reports or analysis.
  5. Excellent oral and written presentation skills; ability to write and present for a variety of audiences.
  6. Demonstrated highly developed organizational skills.
  7. May require highly developed negotiation skills.
  8. Knowledgeable of computer programs needed for position.

Essential Functions

Project management activities to include the development and initiation of an organization wide clinical trials support structure; corresponding process development; and technical supporting the selection and implementation of a clinical trials management system. Project activities will focus on the following elements:

  • Medicare Coverage Analysis and Related Support – A process that ensures that Medicare Coverage Analyses are completed for all appropriate studies, including the entering the appropriate codes for items and services to complete the Billing Grid and determining if conventional care items/services qualify for Medicare coverage.
  • Clinical Trials Registry and Other Document Management -A process to coordinate with Research Teams to validate the study and patient data in the Registry and to ensure data is consistent with the billing system and the IRB database.
  • Budgeting Oversight- A process to review clinical trial study budgets to ensure these budgets are developed in accordance with approved systems, tools and standards.
  • Study Feasibility and Resource Meetings- A process to establish resource meetings with study teams to review the MCA, budget, other study documents, and to make conventional care determinations to complete the final draft of the MCA.
  • Study Approvals- A process to coordinate with the scientific review committee, the IRB and other internal /external parties to ensure that all required approvals are received prior to study initiation.
  • Bill Review- A process to facilitate segregation of items and services provided to research patients utilizing the Medicare Coverage Analysis billing grid and other medical documentation which ensures that either the patient or the research account was billed appropriately for clinical trial related items and services.
  • Study Management- A process to ensure that accounting activities, such as tracking patient/study milestones, reconciling accounts, processing and approving study bills, invoicing sponsors, and reviewing account status with PIs are completed.

Research Assistant III –  Nadeau Lab

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Position Summary

Conducts a variety of laboratory procedures under the general supervision of the principal investigator or the PI’s designee. Assist biological and medical scientists in laboratories. Set up, operate, and maintain laboratory instruments and equipment, monitor experiments, make observations, and calculate and record results. Must be able to recognize problems or deviations in experimental conditions and notify appropriate personnel. Masters routine techniques and procedures relevant to overall goals of the lab. Position availability is directly related to grant funding.

The ideal candidate will have experience in mouse reproduction and genetics as well as with mouse breeding, genotyping, record keeping, and data analysis. This position will work closely with the Principal Investigator, Dr. Joseph Nadeau, to plan the work and analyze results. Specifically, this person will be responsible for setting-up the test and control crosses, conducting the embryo, ovary and sperm assays, including scoring embryo number, viability, sex and genotype; for counting corpora lutea and testing the fit between number of ovulated eggs and litter size; and for assessing sperm number, genotype, morphology, and swimming. As needed, Dr. Nadeau will provide (or arrange) additional training.

Minimum Knowledge, Skills, and Abilities Required

  1. Demonstrated ability above that of a Research Assistant II.
  2. Interpersonal skills necessary to communicate and work effectively.
  3. Visual acuity, manual dexterity, math skills and a scientific acumen are required.
  4. Bachelor’s degree in a relevant field.
  5. 2 + years of relevant experience.

Research Coordinator II 

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This is a per diem position that will support all aspects of investigator initiated research and quality improvement projects in the Department of Psychiatry at Maine Medical Center and the Center for Psychiatric Research at Maine Medical Center Research Institute. Familiarity with DSM-V research diagnostic criteria and some standard psychiatric research diagnostic instruments are a plus. 

Position Summary

This is a clinical and technical position responsible for coordinating clinical research.

Minimum Knowledge, Skills, and Abilities Required

  1. Bachelor’s degree in a health science or related field required.
  2. Knowledge of basic statistical principles and methods.
  3. Ability to function independently and as part of a team.
  4. Excellent communication skills, verbal and written.
  5. 2 years of clinical experience in a healthcare setting required.
  6. Demonstrable computer competency in Microsoft Word and Excel.
  7. Certification by the Association of Clinical Research Professionals or Society of Clinical Research Associates preferred.

Research Coordinator II – Psychiatric Research

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This is a per diem position that will support all aspects of investigator initiated research and quality improvement projects in the Department of Psychiatry at Maine Medical Center and the Center for Psychiatric Research at Maine Medical Center Research Institute. Familiarity with DSM-V research diagnostic criteria and some standard psychiatric research diagnostic instruments are a plus. 

Position Summary

This is a clinical and technical position responsible for coordinating clinical research.

Minimum Knowledge, Skills, and Abilities Required

  1. Bachelor’s degree in a health science or related field required.
  2. Knowledge of basic statistical principles and methods.
  3. Ability to function independently and as part of a team.
  4. Excellent communication skills, verbal and written.
  5. 2 years of clinical experience in a healthcare setting required.
  6. Demonstrable computer competency in Microsoft Word and Excel.
  7. Certification by the Association of Clinical Research Professionals or Society of Clinical Research Associates preferred.

Research Fellow –  Hernandez Lab

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Position Summary

Conducts a variety of complex laboratory procedures and is able to conduct independent research in consultation with the principal investigator.  The research fellow has a sufficient level of experience, expertise and independence to conduct a defined research project, in coordination with the fellows dissertation to be responsible for its inception, implementation and completion with reporting of results in a peer reviewed forum.

Desired Profile

The successful candidate will work in the laboratory of Arturo Hernandez at Maine Medical Center Research Institute. Research projects will involve the use of transgenic mouse and cell culture models to delineate the pathophysiological consequences and underlying mechanisms by which developmental overexposure to thyroid hormones leads to disease in later life, and also in non-exposed subsequent generations via epigenetic mechanisms. The laboratory focuses on endpoints relevant to complex endocrine, developmental and neurobehavioral conditions in humans including autism, schizophrenia, depression, congenital defects, obesity and infertility.  The candidate is expected to be a motivated individual that has recently completed or is close to complete his/her Ph.D. The candidate should have a strong background in biochemistry, molecular and cellular biology, and genetics.  Experience in one or more of the following fields, including endocrinology, neuroscience, epigenetics, developmental biology, thyroid hormone physiology and/or bioinformatics, will be valued.

Minimum Knowledge, Skills, and Abilities Required

  1. A doctoral degree (e.g. PhD, MD, DO, DVM, PharmD)
  2. The ability to comply with research regulations, standards, and policies, and established skills in good laboratory practice, data collection and analysis.
  3. Communication skills that are sufficiently developed that the individual at this level will be able to present research results orally and in written form.

Essential Functions

  1. Conducts complex laboratory procedures and analyses using a variety of manual techniques and laboratory instrumentation. The research fellow may serve as a laboratory or institute resource as a principal user or expert in a specialized instrument or technology
  2. Collaborates with the Principal Investigator and other institute investigators as part of the overall responsibility for project inception and completion
  3. Participates in the training of undergraduates, summer students and other laboratory and institute personnel in candidate’s areas of expertise.
  4. Stays current in literature relevant to area of research interest and expertise.
  5. May provide substantial input, both data and its interpretation, in the preparation of both manuscripts and grants.
  6. Contributes to the interpretation and presentation of research results in manuscript form for publication or in presentations at regional, national or international scientific meetings.

Situated on the Maine coast, Portland offers the best of urban sophistication combined with seaside charm.  The Old Port area receives tourists from around the world with nationally recognized restaurants, breweries, and hotels. In fact, Portland was recently named “2018 Restaurant City of the Year” by Bon Appétit Magazine. The area has an active outdoor community providing four-season recreational opportunities such as skiing, hiking, sailing, and miles of beautiful beaches.  Just two hours north of Boston, this is an exceptionally diverse and vibrant community.

Research Fellow –  Myocardial Biology & Heart Failure Lab

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Position Summary

We are currently recruiting a highly motivated PhD-level scientist to elucidate the role of neuregulin-1/ErbB signaling in the regulation of inflammation and cardiac repair after myocardial ischemic injury. Neuregulins (NRGs) belongs to the epidermal growth factor (EGF) superfamily of transmembrane growth factors. NRG-1 has been intensively studied due to its essential role in cardiac development and in the regulation of the adult cardiovascular system adaptation to physiological and pathological stress. Monocytes express ERBB receptors and neuregulin-1 signaling pathway in myeloid cells contributes to the resolution of inflammation.

We are looking for a qualified individual capable of combining skills in Molecular Biology, Immunology, Molecular Pharmacology and Biochemistry with the ability to work as a team and lead scientific projects in the field.

Minimum Knowledge, Skills, and Abilities Required

  • Applicants must have a Ph.D. in Biotechnology, Pharmacology, Biochemistry, Molecular Biology, or    related area, focusing on molecular studies of signaling pathways relevant in human pathology.
  • In addition, expertise in flow cytometry, isolation of primary cardiac cells, cloning and plasmid production techniques, general molecular biology techniques is required. Knowledge of the English language is desirable.
  • The candidate should have a record of publications in peer review journals.

Research Fellow –  Psychiatric Research

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Maine Medical Center is seeking a Postdoctoral Research Fellow for a well-established and growing early psychosis clinic and research program in Portland, Maine. Start date is flexible between December, 2019 and August, 2020 and the position will remain open until the right candidate is found.

Position Summary

The position, working closely with Dr. Kristen Woodberry at the Maine Medical Center Research Institute, will include a rich combination of clinical work and research with adolescents and young adults in the first couple years of a psychotic disorder or at clinical high risk for psychosis. The affiliated SAMHSA-funded first episode program, PIER, provides coordinated specialty care including multifamily group psychoeducation, CBT for psychosis, case management, supported education and employment, and peer mentorship.

The Research Fellow conducts a variety of complex research procedures and is able to conduct independent research in consultation with the principal investigator. The research fellow has a sufficient level of experience, expertise and independence to conduct a defined research project and report results in a peer reviewed forum.

The ideal candidate will have relevant experience and be looking to develop an independent research career in early psychosis, but will have opportunity to complete hours for licensing and obtain specialized training in assessment and early psychosis treatments. The current research program isfocused on three project areas: 1) identifying dynamic predictors of psychosis, clinical trajectories, and suicide risk using experience sampling; 2) establishing psychosis screening norms for adolescents and screening protocols for use in primary care settings; and 3) development of videogame-based interventions for youth at risk for or in the first years of a psychotic disorder. Opportunities are also available to work with collaborative projects and databases, including studies of stigma, autism, social functioning, and social context. The person hired will have a major role in the experience sampling study,and will be supported in taking leadership, publishing, and seeking independent funding for research within these project areas or in a complementary area.

Essential Functions

  • Conducts complex research procedures and analyses using a variety of techniques and instrumentation. The research fellow may serve as an institute resource as a principal user or expert in a specialized instrument or technology.
  • Collaborates with the PI and other institute investigators as part of the overall responsibility for project inception and completion.
  • Participates in the training of undergraduates, summer students and institute personnel at all levels in the research fellow’s area of expertise.
  • Stays current in literature relevant to area of research interest and expertise. May present research results at regional or national conferences.
  • May provide substantial input, both data and its interpretation, in the preparation of both manuscripts and grants.
  • Will be proactive in identifying, reporting and participating in the resolution of any potential or actual patient safety issues.
  • Prepares advanced training of personnel in the use of key technology or software.
  • Interprets and presents research results in manuscript form where the research fellow has been the principal participant in a research project.

Qualifications

  • PhD in the social sciences or other relevant field.
  • Communication skills to present research results at regional and national research conferences.
  • Demonstrated level of independence to perform research responsibilities.

Ideal candidate will have the following:

  • A recent PhD in clinical psychology or related field.
  • Training and/or experience with adolescents and young adults and with individuals experiencing psychotic symptoms and mood or psychotic disorders.
  • Specific training and experience in specialized early psychosis clinical care or research.
  • Training and experience with structured clinical assessments commonly used with early psychosis populations such as the Structured Clinical Interview of DSM-IV or 5 Disorders (SCID), the Structured Interview of Psychosis-risk Syndromes (SIPS), the Comprehensive Assessment of At-Risk Mental States (CAARMS), the Schizophrenia Proneness Instrument, Adult (SPIA) or Child and Youth (SPICY) versions, the Global Functioning Social and Role Scales (GF-S, GF-R).
  • Specific training or experience in experience sampling, research into the biological correlates of affect or affect variability, sleep, psychosis screening, primary and integrated care, clinical trials, suicide risk or self-harm research, or therapeutic video games.
  • Strong statistical analysis skills and capacity to learn and apply new analytic techniques.

Technology Manager – Mass Spectrometry

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Job Details:

We are seeking an experienced scientist to manage and execute projects within our mass spectrometry core facility at Maine Medical Center Research Institute. This shared resource focuses on state-of-the art protein and lipid analyses using Sciex instrumentation platforms and software. This individual’s primary role will be to work with the Director of the facility to manage all aspects of ongoing projects involving proteomics and lipidomics analysis. Responsibilities will include using biochemical, cell and molecular biology techniques to prepare tissue and cell samples for mass spectrometric quantitative analysis of protein and/or metabolic intermediates. The ideal candidate will have a MS or PhD degree in a related discipline, with working knowledge of Sciex mass spectrometry instrumentation.

The ideal candidate will:

  1. Have training in mass spectrometry techniques and related instrumentation.
  2. Have training in basic and analytical biochemistry, molecular and cell biology.
  3. Self-starter, intellectually engaged in the science and technology development, and able to work independently to troubleshoot problems and analyze the data obtained from mass spectrometry experiments.
  4. Have good organizational and personnel management skills.
  5. Able to work with a variety of researchers to help design and implement projects.

* This is a grant funded position

Position Summary

This individual’s primary responsibility will be to manage applications of nano- and micro-scale liquid chromatography and mass spectrometry. This includes, but is not limited to oversight of using this technology, maintenance of the instrumentation, overall technical and quality assurance operations, supply management, and training and instruction of the technology. May or may not have direct supervisory responsibility depending on the requirements of the project or program. Supported by grant funding that includes NIH funding or our Center of Biomedical Research Excellence.

Required Minimum Knowledge, Skills, and Abilities

  • Ph.D. or M.S. plus experience or a B.S. in a specialized related field.
  • A minimum of 2 years of directly related experience.
  • May be proficient in operation of one or more applications within a specific technology. Skills should include ability to troubleshoot problems and analyze the data obtained from instrumentation.
  • Certifications based on technology, if applicable.
  • Must have good organizational and personnel management skills.
  • Project management skills, communication skills, both personal and written, business skills and schedule planning acumen.
  • Visual acuity, manual dexterity, math skills and a scientific acumen required.

Temporary Research Coordinator II – Oncology

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Position Summary

This is a great opportunity to work as part of the busy Clinical Trials Office at Maine Medical Center Research Center. We are searching for someone to help cover the workload of a staff member out on medical leave. Ideally, we would like someone full time but we can be flexible about hours worked per week based on candidate availability. The position is located in Adult Oncology and the primary responsibilities will include assisting Research Coordinators and completing regulatory submissions. It is anticipated that the position will last at least several months, possibly longer, based on the needs of the department.

Required Minimum Knowledge, Skills, and Abilities

  • Bachelor’s degree in a health science field required.
  • Knowledge of basic statistical principles and methods.
  • Ability to function independently and as part of a team.
  • Excellent communication skills, verbal and written.
  • 2 years of clinical experience in a healthcare setting required.
  • Demonstrable computer competency in Microsoft Word and Excel.
  • Certification by the Association of Clinical Research Professionals or Society of Clinical Research Associates preferred.