Donald L. St. Germain, MD

Vice President, Research, Maine Medical Center
Director, Maine Medical Center Research Institute

Dr. St. Germain was appointed Director of MMCRI and VP for Research at Maine Medical Center in 2009.  He received a B.S. degree (magna cum laude) in Chemical Engineering from Louisiana State University in 1972 and subsequently attended the Johns Hopkins University School of Medicine where he received the M.D. degree in 1976. He completed his clinical training in Internal Medicine and Endocrinology at University Hospitals of Cleveland in 1980, and subsequently served as Chief Resident in Internal Medicine at Dartmouth-Hitchcock Medical Center (DHMC).

In 1981, he undertook a postdoctoral research fellowship in the Departments of Medicine and Physiology at Dartmouth Medical School where he trained with Dr. Valerie Anne Galton and Dr. Robert Adler. He was appointed to the faculty of Dartmouth Medical School in 1984.

Dr. St. Germain’s research program has centered on investigating the molecular mechanisms involved in the metabolism and action of thyroid hormones, with a particular focus on the developmental and neurological effects of these native compounds. In this regard, Dr. St. Germain and his colleagues have developed and are studying a number of transgenic mouse lines with altered expression of the deiodinase enzymes, which regulate thyroid hormone levels during fetal and neonatal life.

Since being recruited to Maine Medical Center Dr. St. Germain has overseen an expansion of research activities across the Organization, including the institution of novel programs to support and foster translational and clinical research programs that are benefitting the patients of Maine and strengthening the academic stature and the national visibility of the Institution.