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Faculty Scientist II- Health Outcomes/Health Services Research

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Job Details

  • The ideal candidate for this position will be a health outcomes researcher with a substantive focus in one or more of the following areas: health communication, decision sciences/medical decision making, health services research, or a related field of inquiry.
  • Mid-career researchers with an established program of research and a strong track record of extramural funding and peer-reviewed publications are preferred; however, early career candidates with appropriate skills and experience will be considered.
  • Candidates with an MD/DO, PhD, ScD, DrPH, or other relevant doctoral degree will be considered for this position. For physician-scientists, candidates with formal research training (e.g., MPH, research fellowship) are strongly preferred.

Position Summary

Conducts a variety of research activities, often heading projects independently, but may enlist the assistance of more experienced scientists as collaborators. This position will receive mentorship from one or more senior scientists in areas such as grant writing and applications, teaching, and navigating research administration and research compliance issues. This position will be responsible for the independent conception of research projects, obtaining external funding for these projects and the publication of results from these projects in a timely manner. These studies should be of sufficient importance and impact to bring recognition to the investigator, resulting in increased or sustained funding, etc. This individual will assist in the development of operational guidelines for the research. As an independent position, the individual should exercise good judgment in decision making with regard to the management of personnel, budgets, and other matters that pertain to running a program or project as an independent investigator. With regard to problem-solving, the individual in this position should know the limitations of his or her problem solving skills both scientifically and administratively and should use good judgment to seek advice and input from reliable sources when the problem is beyond the scope of his or her expertise. Follows safety, human subjects and animal use guidelines. Manages grants or projects including supervision of multiple staff, project reports, etc. Monitors the project budget. Where inventions or other intellectual property are developed during the course of the research, will contribute to the process of working with the patents and licensing office to seek appropriate rights. Ability to supervise and to coordinate efforts of several staff for complex internal/external groups. Position availability is directly related to grant funding.

Minimum Knowledge, Skills, and Abilities Required

  • Demonstrated ability to read, write, and speak English effectively
  • Excellent written and verbal communication skills
  • Outstanding interpersonal skills
  • Visual acuity, manual dexterity, math skills and a scientific acumen are required.
    Doctoral degree in relevant biomedical discipline
  • 5 years of experience as a Faculty Scientist I (or Assist Prof)
    Successful track record of R01 funding or equivalent research support
  • First or Senior author publications in major peer-reviewed biomedical journals
  • Evidence of beginning of national recognition in selected field as demonstrated by invited presentations at national biomedical meetings and invited reviews for major biomedical publications
  • Demonstrated ability to design and conduct novel and potentially high impact biomedical experiments
  • Evidence of significant mentorship and teaching accomplishments
  • Evidence of significant institutional citizenship

Essential Functions

  • Supervises major research project(s) and writes grants and obtains extramural funding for major research projects.
  • Ensures timely, accurate and complete communication of research findings at regional, national and international meetings and in major and specialty-specific biomedical journals.
  • Teaches and mentors (as assigned by Center Director) summer students, interns, graduate student and research fellows.
  • Serves on Institutional committees (as assigned by Director, MMCRI) and participates in regional and national professional societies and activities.
  • Ensures compliance with all state and federal regulations pertaining to safety, the ethical conduct of research, financial reporting to funding agencies, and standards of professional conduct.
  • Promotes teamwork and collaboration within MMCRI and with outside institutions.

Research Assistant II – Psychiatric Research

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Job Details

The Research Assistant II (RA II) will support a nationally recognized Autism Spectrum Disorders research program.  The RA II will take the lead in participant recruitment, screening, consent, and data collection for a clinical trial studying the effectiveness of Therapeutic Horseback Riding (THR) for children with a diagnosis of Autism Spectrum Disorder. Candidates should have experience in recruitment and consenting of research participants. Candidates must be comfortable speaking with families in person and over the phone and have interest and capability to conduct study activity on site at a horse riding center in Windham, Maine.  The latter will require the candidate to be unaffected by animal/barn related allergies, and to provide his/her own transportation to and from the center. The position will involve collection and computer data entry of assessment measures, and collection of physiological data using biosensors worn by the participant.  The position requires good people skills, attention to detail, the ability to work at a computer for long periods of time, and of key importance is comfort interacting closely with children who at times may have dysregulated emotion and behavior. Experience with children who have Autism or other special needs is preferred.

Position Summary

Conduct a variety of research activities related to the collection, entry, and organization of data under the general supervision of the principal investigator (PI) or senior staff. Assist the PI and team members working in areas such as psychology, psychiatry, and clinical intervention research, in clinic and community-based studies.  Set up, maintain, and operate data bases and computer equipment. Must be able to recognize problems or deviations from the experimental design and protocol and notify appropriate staff.  Master routine data collection procedures and analysis techniques to achieve the overall goals of the study. Position availability is directly related to grant funding.

Minimum Knowledge, Skills, and Abilities Required

  1. Demonstrated ability above that of a Research Assistant I.
  2. Ability to use a computer and statistical software packages, to collect and enter data.
  3. Interpersonal skills necessary to communicate and work effectively with others. 
  4. Visual acuity, manual dexterity, math skills and a scientific acumen are required.
  5. Bachelor’s degree in a related field.
  6. 1+ years of relevant experience.

Research Assistant III – Nadeau Lab

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Position Summary

Conducts a variety of laboratory procedures under the general supervision of the principal investigator or the PI’s designee. Assist biological and medical scientists in laboratories. Set up, operate, and maintain laboratory instruments and equipment, monitor experiments, make observations, and calculate and record results. Must be able to recognize problems or deviations in experimental conditions and notify appropriate personnel. Masters routine techniques and procedures relevant to overall goals of the lab. Position availability is directly related to grant funding.

The ideal candidate will have experience in mouse reproduction and genetics as well as with mouse breeding, genotyping, record keeping, and data analysis. This position will work closely with the Principal Investigator, Dr. Joseph Nadeau, to plan the work and analyze results. Specifically, this person will be responsible for setting-up the test and control crosses, conducting the embryo, ovary and sperm assays.  As needed, Dr. Nadeau will provide (or arrange) additional training.

Minimum Knowledge, Skills, and Abilities Required

  1. Demonstrated ability above that of a Research Assistant II.
  2. Interpersonal skills necessary to communicate and work effectively.
  3. Visual acuity, manual dexterity, math skills and a scientific acumen are required.
  4. Bachelor’s degree in a relevant field.
  5. 2 + years of relevant experience.

Research Associate I – Liaw Lab

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Job Details

The successful candidate will have a strong background in cell biology, laboratory techniques, laboratory math, basic statistics, and standard office software such as Word, Excel, and PowerPoint. Interest in learning new software/analyses is required. This individual will perform basic laboratory maintenance chores: preparation of stock solutions, cell culture media, buffers; maintenance of lab equipment and chemical and biological substance inventories, and will be expected to actively participate in a collaborative lab team environment. Responsibilities include processing tissues and cells derived from human surgical samples, and maintaining primary cell cultures. Precise documentation and record keeping ability is vital. Other responsibilities will include cell-based assays, and isolation of RNA and protein for downstream analyses, and tissue process for histological and microscopy analyses. Excellent communication and collaboration skills needed.

Position Summary

Conducts a variety of complex laboratory procedures and is able to conduct independent research in consultation with the principal investigator. The research associate has a sufficient level of experience, expertise and independence to conduct a defined research project with overall responsibility for its inception, implementation and completion with reporting of results in a peer reviewed forum. Position availability is directly related to grant funding.

Minimum Knowledge, Skills, and Abilities Required

  • Demonstrated ability above that of a Research Assistant III.
  • Communication skills that are sufficiently developed that the individual at this level will be able to present research results at regional and national research conferences.
  • Visual acuity, manual dexterity, math skills and a scientific acumen are required.
  • Bachelor’s degree in a relevant field, Master’s degree preferred.
  • 2 + years of relevant experience with Master’s degree, 3+  years with Bachelor’s degree.

Research Associate I – Mouse Genome Modification Core Facility

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Job Details

The successful candidate will have basic knowledge in mammalian genetics, as well as a strong background in molecular biology, laboratory techniques, laboratory math, and standard office software including Word, Excel, and PowerPoint. Interest in learning new software/analyses is required. This position will be responsible for performing basic laboratory maintenance chores and actively participating as part of a collaborative lab team environment. This staff member will be part of our molecular biology service within our Mouse Genome Modification Core Facility, and will need meticulous documentation skills. The position will require analysis of genomic sequences, DNA isolation and cloning, PCR, genotyping, other basic molecular biology techniques, and use of software and available databases for gene/sequence analysis. There is an opportunity to gain experience in mouse colony maintenance, reproductive surgical procedures and methods for transgenesis. Excellent communication and collaboration skills needed.

Position Summary

Conducts a variety of complex laboratory procedures and is able to conduct independent research in consultation with the principal investigator. The research associate has a sufficient level of experience, expertise and independence to conduct a defined research project with overall responsibility for its inception, implementation and completion with reporting of results in a peer reviewed forum. Position availability is directly related to grant funding.

Minimum Knowledge, Skills, and Abilities Required

  • Demonstrated ability above that of a Research Assistant III.
  • Communication skills that are sufficiently developed that the individual at this level will be able to present research results at regional and national research conferences.
  • Visual acuity, manual dexterity, math skills and a scientific acumen are required.
  • Bachelor’s degree in a relevant field, Master’s degree preferred.
  • 2 + years of relevant experience with Master’s degree, 3+  years with Bachelor’s degree.

Research Coordinator II – Psychiatric Research

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This is a per diem position that will support all aspects of investigator initiated research and quality improvement projects in the Department of Psychiatry at Maine Medical Center and the Center for Psychiatric Research at Maine Medical Center Research Institute. Familiarity with DSM-V research diagnostic criteria and some standard psychiatric research diagnostic instruments are a plus. 

Position Summary

This is a clinical and technical position responsible for coordinating clinical research.

Minimum Knowledge, Skills, and Abilities Required

  1. Bachelor’s degree in a health science or related field required.
  2. Knowledge of basic statistical principles and methods.
  3. Ability to function independently and as part of a team.
  4. Excellent communication skills, verbal and written.
  5. 2 years of clinical experience in a healthcare setting required.
  6. Demonstrable computer competency in Microsoft Word and Excel.
  7. Certification by the Association of Clinical Research Professionals or Society of Clinical Research Associates preferred.

Research Fellow – Hernandez Lab

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Position Summary

 
Conducts a variety of complex laboratory procedures and is able to conduct independent research in consultation with the principal investigator.  The research fellow has a sufficient level of experience, expertise and independence to conduct a defined research project, including project inception and design, implementation, and completion, with reporting of results in a peer reviewed forum consisting of oral and written presentation.
 
The successful candidate will work in the laboratory of Arturo Hernandez at Maine Medical Center Research Institute. Research projects will involve the use of transgenic mouse and cell culture models to delineate the pathophysiological consequences and underlying mechanisms by which developmental overexposure to thyroid hormones leads to disease in later life, and also in non-exposed subsequent generations via epigenetic mechanisms. The laboratory focuses on endpoints relevant to complex endocrine, developmental and neurobehavioral conditions in humans including autism, schizophrenia, depression, congenital defects, obesity and infertility.  The candidate is expected to be a motivated individual that has recently completed or is close to complete his/her Ph.D. The candidate should have a strong background in biochemistry, molecular and cellular biology, and genetics.  Experience in one or more of the following fields, including endocrinology, neuroscience, epigenetics, developmental biology, thyroid hormone physiology and/or bioinformatics, will be valued.

Minimum Knowledge, Skills, and Abilities Required

  1. A doctoral degree (e.g. PhD, MD, DO, DVM, PharmD).
  2. The ability to comply with research regulations, standards, and policies, and established skills in good laboratory practice, data collection and analysis.
  3. Communication skills that are sufficiently developed that the individual at this level will be able to present research results orally and in written form.

Essential Functions

Job Knowledge

  • Conducts complex laboratory procedures and analyses using a variety of manual techniques and laboratory instrumentation.
  • Collects data and is competent in data storage, analysis, statistical analysis, and data visualization.

Collaboration

  • Collaborates with the PI and other institute investigators as part of the overall responsibility for project inception and completion.
  • Promotes a culture of equity and inclusion

Education and Development

  • Participates in the training of undergraduates, summer students, graduate students and institute personnel at all levels in the research associates area of expertise, including advanced training on use of institute instrumentation cores where applicable.
  • Stays current in literature relevant to area of research interest and expertise. May present research results at institutional meetings and at local, regional, or national conferences.

Data Management/Reporting

  • May provide substantial input, both data and its interpretation, in the preparation of both manuscripts and grants.
  • Interprets and presents research results in manuscript form where the research fellow has been the principal participant in a research project.

Other

  • Will be proactive in identifying, reporting and participating in the resolution of any potential or actual safety issues.

Research Fellow- Liaw Lab

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Job Details

We are seeking a motivated, creative, postdoctoral fellow to join a basic/translational research team focused on cardiometabolic disease. We study signaling mechanisms related to development of cardiovascular disease, and the impact of local adipose tissue on cells of the vessel wall. Our experimental approaches include analysis using cell and molecular biology techniques, genetic mouse models, derivation and study of primary cell cultures, analysis of human disease specimens and relation to clinical phenotype, and proteomics analysis of molecular signatures to define unique disease profiles. Competency and desire to develop expertise in these areas will be supported. The successful candidate will have a strong foundation in research design, data analysis, manuscript writing and publication, oral presentation of research, and have strong communication and documentation skills. This individual is expected to contribute to the efficient functioning of a research lab as well as develop and implement her/his own research project. Our lab team has an additional interest in mentorship and outreach, and in communicating science and research as a benefit to our society.

Position Summary

Conducts a variety of complex laboratory procedures and is able to conduct independent research in consultation with the principal investigator.  The research fellow has a sufficient level of experience, expertise and independence to conduct a defined research project, in coordination with the fellow’s dissertation to be responsible for its inception, implementation and completion with reporting of results in a peer reviewed forum.

Minimum Knowledge, Skills, and Abilities Required

  • Education: Candidate for a Ph.D. in biology, chemistry.
  • License/Certifications: N/A
  • Experience: N/A
  • Communication skills that are sufficiently developed that the individual at this level will be able to present research results at regional and national research conferences.
  • The research fellow will have demonstrated a level of independence to perform laboratory responsibilities.

Technology Manager – Mass Spectrometry

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Job Details:

We are seeking an experienced scientist to manage and execute projects within our mass spectrometry core facility at Maine Medical Center Research Institute. This shared resource focuses on state-of-the art protein and lipid analyses using Sciex instrumentation platforms and software. This individual’s primary role will be to work with the Director of the facility to manage all aspects of ongoing projects involving proteomics and lipidomics analysis. Responsibilities will include using biochemical, cell and molecular biology techniques to prepare tissue and cell samples for mass spectrometric quantitative analysis of protein and/or metabolic intermediates. The ideal candidate will have a MS or PhD degree in a related discipline, with working knowledge of Sciex mass spectrometry instrumentation; however, candidates with related skills and experience should contact Dr. Cal Vary for a conversation about a possible fit for the position:  varyc@mmc.org.

The ideal candidate will:

  1. Have training in mass spectrometry techniques and related instrumentation.
  2. Have training in basic and analytical biochemistry, molecular and cell biology.
  3. Self-starter, intellectually engaged in the science and technology development, and able to work independently to troubleshoot problems and analyze the data obtained from mass spectrometry experiments.
  4. Have good organizational and personnel management skills.
  5. Able to work with a variety of researchers to help design and implement projects.

* This is a grant funded position

Position Summary

This individual’s primary responsibility will be to manage applications of nano- and micro-scale liquid chromatography and mass spectrometry. This includes, but is not limited to oversight of using this technology, maintenance of the instrumentation, overall technical and quality assurance operations, supply management, and training and instruction of the technology. May or may not have direct supervisory responsibility depending on the requirements of the project or program. Supported by grant funding that includes NIH funding or our Center of Biomedical Research Excellence.

Required Minimum Knowledge, Skills, and Abilities

  • Ph.D. or M.S. plus experience or a B.S. in a specialized related field.
  • A minimum of 2 years of directly related experience.
  • May be proficient in operation of one or more applications within a specific technology. Skills should include ability to troubleshoot problems and analyze the data obtained from instrumentation.
  • Certifications based on technology, if applicable.
  • Must have good organizational and personnel management skills.
  • Project management skills, communication skills, both personal and written, business skills and schedule planning acumen.
  • Visual acuity, manual dexterity, math skills and a scientific acumen required.